PUBLICATIONS:
1. Original observations in refereed journals:
Angela G. Vouyouka, MD. Richard J Powell, MD, Joseph Ricotta MS, Daniel Dudrick MS, Stanley Dudrick, MD, Bauer E. Sumpio MD, Ph.D. Ambient Pulsatile Pressure Modulates the Endothelial Cell Proliferation. Journal of Cellular & molecular Cardiology, 1998 Mar; 30(3): 609-615,
Liem TK, Vouyouka A, Dixon J, Shukla S, Silver D, Krause G, Sturek MS. Diabetes enhances the uptake of cholesterol in low shear regions. Surgical Forum 1999; Vol 50: 429-432.
Angela G. Vouyouka, MD, Brent J. Pfeiffer, BS Timothy K. Liem, MD, Timothy A. Taylor, PhD, Junaid Mudaliar, MD, and Charlotte L. Phillips, PhD: The role of type I collagen in aortic wall strength using a homotrimeric (a1(I)]3 collagen mouse model. J Vasc Surg 2001; 33:1263-1270.
Angela G. Vouyouka MD, Shady Selim Salib, Stephen Cala, James D.Marsh and Marc D. Basson: Chronic High Pressure Potentiates the Anti-Proliferative Effect and Abolishes Contractile Phenotypic Changes Caused by Endothelial Cells in Cocultured Smooth Muscle Cells.J Surg Res. 2003 Apr; 110(2): 344-351.
Angela G. Vouyouka, MD, Yan Jiang MS, Marc D. Basson MD, PhD: Pressure alters endothelial effects upon vascular smooth muscle cells (SMC) by decreasing smooth muscle cell proliferation and increasing smooth muscle cell apoptosis. Surgery 2004 136(2): p. 282-290.
Agelikie G. Vouyouka, MD, Lifeng Li MS, Marc Basson MD PhD: Pressure and endothelial coculture upregulate myocytic Fas-FasL pathway and induce apoptosis via direct and paracrine mechanisms. The Ame J of Surgery 190 (2005) 780-786.
David Lau MD, Kenneth Granke MD Ronke Olabisi MS, Marc D. Basson MD, PhD, Agelikie Vouyouka MD ?Carotid endarterectomy in Octagenarian Veterans: Does age affect outcome a single center experience. The Ame J of Surgery 190(2005), 795-799.
Kumar Rajamani MD, Mohammed Sunbulli MD, Bradley S. Jacobs MD, Elizabeth Berlow RN, James D. Marsh MD, Marvin W. Kronenberg MD, Patrick McLaughlin MD, Angela Vouyouka MD, Steven R. Levine MD Zongshan Lai MPH and Seemant Chaturvedi MD: Detection of carotid stenosis in African Americans with ischemic heart disease . J Vasc Surg 43(6) Jun 2006 1162-1165
Angela G. Vouyouka MD Yan Jiang MS Ruchi Rastogi MS and Marc Basson MD PhD: Ambient pressure up regulates nitric oxide synthase in a p-ERK and PKC dependent manner. J Vasc Surg 2006;44:1076-1084.
2. Review articles:
Angela Vouyouka MD, Donald Silver MD: is low Molecular ?Weight Heparin the Answer for the Therapy of Acute Deep Vein Thrombosis? -Expert Commentary. Vascular Surgery vol.33 (2): 125-128, March/ April 1999.
Donald Silver MD, Angela Vouyouka MD: The caput medusae of hypercoagulability. J Vasc Surg 2000;31:396-405
3. Books and Chapters:
Silver D, Vouyouka AG: Management of Venous Thromboembolism. In Mastery of Surgery, 4th edition. LM Nyhus, RJ Baker, JE Fischer, Editors Little, Brown and Company Boston Mass
Angela Vouyouka MD, Donald Silver MD: ?Heparin-induced complications? In Decision making in Vascular Surgery, 2001 W>B> Saunders Company.
4. Published Abstracts;
A.Vouyouka, H. Chen, B.E. Sumpio. Effects of Pulsatile Pressure on Endothelial Cell Phenotype The FASEB Journal 1995, Volume 9, Number 3 A314:1821 (abstract)
H.A. Chen, A. Vouyouka M.A. Awolesi C. Sawmiller and B.E. Sumpio. Nitric Oxide Production by Endothelial Cells (EC) Grown in Ambient Static or Pulsatile pressure in Vitro Lack of Effect on EC Proliferation. The FASEB Journal 1997, Volume 11, Number 3 A223: 1295 (abstract).
Charlotte L Phillips, Angela G. Vouyouka, Brent J. Pfeiffer, Timothy A.
Taylor. University of Missouri - Columbia, Columbia, Missouri, U.S.A. in proceedings of 7th international conference on Osteogenesis Imperfecta 1999
PRESENTATIONS:
? April 95Atlanta, Georgia Experimental Biology 95TM
Effects of Pulsatile Pressure on Endothelial Cell Phenotype
Vouyouka, H. Chen, B.E. Sumpio. (Poster presentation).
? June 95: New Orleans, Louisiana The International Society for Cardiovascular Surgery 43rd Scientific Meeting
Endothelial Cell Growth and TGF-b Are Altered With Static and Pulsatile Pressure in Vitro. Angela Vouyouka, MD. Guangdi LI, MD. Richard Powell, MD, and Bauer Sumpio, MD, Ph.D. (poster presentation).
? Dec. 95: Cromwell, Connecticut/ American College of Surgeons- Connecticut Chapter Meeting
Static and Pulsatile Pressure produce in Vitro Differences in Endothelial cell (EC) Growth Patterns.
? A.G.Vouyouka, MD, D.J. Dudrick, S.J. Dudrick, MD, B.E Sumpio MD, Ph.D. (slide presentation)
? March 96:New York, N.Y. Aortic Surgery Symposium V/The Mount Sinai Center
Significance of Pleural Effusions in Descending Aortic Dissections.
Angela Vouyouka, MD, Kevin Johnson, MD, John Rizzo, PhD, Michael Coady, MD, Jackie Quin, MD, Ellen Frank, MD, MPH, Umer Darr, MD, and John Elefteriades, MD (poster presentation)
? June 96: Barcelona, Spain. American College of Angiology/The 43rd Annual World Assembly
Significance of Pleural Effusions in Descending Aortic Dissections.
Angela Vouyouka, MD, Kevin Johnson, MD, John Rizzo, Ph.D., Michael Coady, MD, Jackie Quin, MD, Ellen Frank, MD, MPH, Umer Darr, MD, and John Elefteriades, MD (slide presentation)
? April 97: New Orleans, LA Experimental Biology 97R
Nitric Oxide Production by Endothelial Cells (EC) Grown in Ambient Static or Pulsatile pressure in Vitro Lack of Effect on EC Proliferation.
H.A. Chen, A.Vouyouka M.A. Awolesi C. Sawmiller and B.E. Sumpio (poster presentation)
? June 99: Lake of the Ozarks, MO American College of Surgeons- Missouri Chapter/ 32nd annual professional meeting
?Diabetes Enhances the Uptake of Cholesterol Uptake in Low Shear Regions.?
Angela G. Vouyouka, MD, Michael Sturek, Ph.D., Timothy K. Liem, MD. (Slide presentation)
? June 99: Lake of the Ozarks, MO. American College of Surgeons- Missouri Chapter/ 32nd annual professional meeting
?Osteogenesis Imperfecta Type III Alters the biomechanical properties of the Aorta? Angela G. Vouyouka MD, Brent Pfeifer MD, Timothy Taylor Ph.D., Charlotte Phillips, Ph.D., Timothy K. Liem, MD (oral presentation)
? October 99: San Francisco, CA American College of Surgeons/ 85th annual Clinical Congress
?Diabetes Enhances the Uptake of Cholesterol in Low Shear Regions?
Timothy K. Liem, MD Angela G. Vouyouka MD, Joseph Dixon, PhD, Shivendra Shukla, PhD, Donald Silver MD, FACS, Gary Krause, PhD, Michael S. Sturek PhD.
? 1999: Montreal Canada, 7th international conference on Osteogenesis Imperfecta
Reduced Biomechanical Strength of the Thoracic Aorta in the OIM (Osteogenesis
Imperfecta Model) Mouse.
Charlotte L Phillips, Angela G. Vouyouka, Brent J. Pfeiffer, Timothy A.
Taylor. University of Missouri - Columbia, Columbia, Missouri, U.S.A.
? April 2002 : Houston TX, Association of VA Surgeons annual meeting
?Chronic high pressure potentiates the antiproliferative effect and abolishes contractile phenotypic changes caused by Endothelial cells (EC?s) in cocultured Smooth muscle cells (SMC?s)?. Shady Salib MD, Marc D. Basson MD, PhD, Stephen Cala PhD, James D. Marsh MD, and Angela G. Vouyouka MD, Departments of Surgery and Cardiology, Wayne State University and John D. Dingell VAMC.-oral presentation
? February 2004: St Louis MO, Society of University Surgeons (SUS) annual meeting ?Pressurized endothelial cell (EC)/ Smooth muscle cell (SMC) co-culture decreases SMC proliferation and Increases SMC apoptosis? Angela G.Vouyouka MD,Yan Jiang MS and Marc D. Basson MD, Ph.D, Departments of Surgery, John D. Dingell VAMC and Wayne State University- oral presentation
? February 2005: New Orleans LO, international stroke conference 2005: Early Identification of African Americans at Increased risk for Stroke? Mohammed Sumbulli, Bradley S Jacobs, Renee B. Van Stavern, Elizabeth Berlow, Angela G. Vouyouka, James Marsh, Patrick McLaughlin, Seemant Chaturvedi Wayne State University, Detroit MI (oral presentation)
? March 2005: Salt Lake city UT, Association of VA Surgeons annual meeting: ?Pressurized Endothelial Cell (EC)/Smooth Muscle Cell (SMC) Co-culture Stimulates SMC Apoptosis by Indirect Panacrine EC and Direct Pressure-Induced Mechanisms that Upregulate Fas and FasL?Angela G. Vouyouka , Lifeng Lin, Marc Basson ( oral presentation)
? March 2005: Salt Lake city UT, Association of VA Surgeons annual meeting:
?Carotid endarterectomy (CEA) in elderly veterans: Does age affect immediate or long term outcome? A single center experience?.David Lau MD, Ronke Olabisi MS, Kenneth Granke MD, Marc D. Basson MD, PhD, Agelikie Vouyouka MD ( oral presentation)
? April 2005 Washington DC, SVS-research initiatives meeting:
?Increased extracellular pressure upregulates nitric oxide synthase in cultured endothelial cells via ERK and PKC.? Angela (Agelikie) G Vouyouka , Lifeng Li Charles Shanley , Marc D. Basson -poster presentation
? May 2006: Cincinnati OH, association of VA surgeons annual meeting:
?Abdominal Aortic Aneurysm Disease in African American Patients: Is Race a Factor??
MD1 Michael Ranella, BS1; Shannon O?Connor, BS2; Suzanne Ohmit, PhD,3Kathleen Litwinczuk, NP1; Marc D Basson, MD, PhD4 Agelikie Vouyouka,(oral presentation)
? May 2006: Cincinnati OH, association of VA surgeons annual meeting:
?Clinical durability of femoro-popliteal angioplasty in veterans: outcome analysis from a single VA center? David Lau MD, Kenneth Granke MD, ,Agelikie Vouyouka MD (poster presentation)



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